Cortical atrophy in young adults with a history of hyperactivity in childhood

Henry A. Nasrallah, Jan Loney, Stephen C. Olson, Mona McCalley-Whitters, John Kramer, Charles G. Jacoby

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


A computed tomographic (CT) brain scan study was conducted in 24 young males treated and followed up for hyperactivity since childhood. Compared to 27 matched controls, adults with a history of hyperactivity had a significantly greater frequency of cerebral atrophy. No differences in cerebellar atrophy frequency or in lateral cerebral ventricle-to-brain ratio (VBR) were found. The possible associations of hyperactivity or perhaps stimulant drug treatment to atrophic brain changes are discussed.

Original languageEnglish (US)
Pages (from-to)241-246
Number of pages6
JournalPsychiatry Research
Issue number3
StatePublished - Mar 1986


  • Computerized tomography
  • cerebellar atrophy
  • cortical atrophy
  • hyperactivity
  • ventricular enlargment


Dive into the research topics of 'Cortical atrophy in young adults with a history of hyperactivity in childhood'. Together they form a unique fingerprint.

Cite this