Cortical atrophy in young adults with a history of hyperactivity in childhood

Henry A. Nasrallah; Jan Loney; Stephen C. Olson; Mona McCalley-Whitters; John Kramer; Charles G. Jacoby

doi:10.1016/0165-1781(86)90052-1

Cortical atrophy in young adults with a history of hyperactivity in childhood

Henry A. Nasrallah, Jan Loney, Stephen C. Olson, Mona McCalley-Whitters, John Kramer, Charles G. Jacoby

Psychiatry & Behavioral Sciences

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43 Scopus citations

Abstract

A computed tomographic (CT) brain scan study was conducted in 24 young males treated and followed up for hyperactivity since childhood. Compared to 27 matched controls, adults with a history of hyperactivity had a significantly greater frequency of cerebral atrophy. No differences in cerebellar atrophy frequency or in lateral cerebral ventricle-to-brain ratio (VBR) were found. The possible associations of hyperactivity or perhaps stimulant drug treatment to atrophic brain changes are discussed.

Original language	English (US)
Pages (from-to)	241-246
Number of pages	6
Journal	Psychiatry Research
Volume	17
Issue number	3
DOIs	https://doi.org/10.1016/0165-1781(86)90052-1
State	Published - Mar 1986

Keywords

Computerized tomography
cerebellar atrophy
cortical atrophy
hyperactivity
ventricular enlargment

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AU - Nasrallah, Henry A.

AU - Loney, Jan

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AU - Kramer, John

AU - Jacoby, Charles G.

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AB - A computed tomographic (CT) brain scan study was conducted in 24 young males treated and followed up for hyperactivity since childhood. Compared to 27 matched controls, adults with a history of hyperactivity had a significantly greater frequency of cerebral atrophy. No differences in cerebellar atrophy frequency or in lateral cerebral ventricle-to-brain ratio (VBR) were found. The possible associations of hyperactivity or perhaps stimulant drug treatment to atrophic brain changes are discussed.

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KW - ventricular enlargment

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Cortical atrophy in young adults with a history of hyperactivity in childhood

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Keywords

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