Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant

Medicine & Life Sciences

• Tacrolimus Binding Protein 1A 100%
• Tandem Repeat Sequences 80%
• Ryanodine Receptor Calcium Release Channel 78%
• Tacrolimus Binding Proteins 69%
• Protein Binding 31%
• B30.2-SPRY Domain 27%
• Excitation Contraction Coupling 20%
• Sarcoplasmic Reticulum 17%
• Molecular Dynamics Simulation 17%
• Mutagenesis 15%
• Endoplasmic Reticulum 15%
• Membranes 9%
• Mutation 8%

Physics & Astronomy

• determinants 66%
• crystal structure 49%
• proteins 30%
• sarcoplasmic reticulum 19%
• mutagenesis 18%
• endoplasmic reticulum 17%
• homology 16%
• mutations 14%
• folding 12%
• calcium 12%
• contraction 11%
• assembly 10%
• membranes 9%
• molecular dynamics 9%
• excitation 6%

Chemical Compounds

• Ryanodine 93%
• Crystal Structure 31%
• Protein 26%
• Mutation 17%
• Calcium(0) 16%
• Molecular Dynamics 15%
• Molecular Cluster 13%