Abstract
Proxy respondents have often been used in case-control studies of cancer and pesticides. To evaluate the effect of exposure misclassification, we compared data collected during 1981–1983 from participants interviewed for a case-control study of leukemia and non-Hodgkin’s lymphoma with data collected during 1990–1991 from proxy respondents for participants who died or became incompetent since the initial interview (328 self-proxy pairs). As questions increased in detail, agreement percentages decreased. Agreement percentages were highest for demographic and general farming information (averages = 88–90%) and lowest for specific pesticide use (averages = 68–74%). Generally, odds ratios calculated from proxy respondent data were less than those from self-respondent data; however, several exceptions occurred. The findings indicate that pesticide data provided by proxy respondents will not necessarily result in the same estimate of risk and/or lead to the same conclusions as data provided by self-respondents.
Original language | English (US) |
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Pages (from-to) | 157-164 |
Number of pages | 8 |
Journal | Epidemiology |
Volume | 4 |
Issue number | 2 |
DOIs | |
State | Published - Mar 1993 |
Keywords
- Data collection
- Epidemiologic methods
- Interviews
- Neoplasms
- Pesticides
- Proxy respondents