Determination of apurinic/apyrimidinic lesions in DNA with high-performance liquid chromatography and tandem mass spectrometry

Medicine & Life Sciences

• Deoxyribose 100%
• Tandem Mass Spectrometry 97%
• High Pressure Liquid Chromatography 73%
• DNA 49%
• Uracil 48%
• Digestion 34%
• O-(biotinylcarbazoylmethyl)hydroxylamine 27%
• Carcinogens 24%
• endoexonuclease 23%
• calf thymus DNA 19%
• Oxidative Stress 18%
• Solid Phase Extraction 17%
• Electrospray Ionization Mass Spectrometry 17%
• Single-Stranded DNA 15%
• Limit of Detection 13%
• Mass Spectrometry 11%
• DNA Damage 11%
• Hot Temperature 9%
• Acids 9%
• Neoplasms 8%
• Mutation 7%

Chemical Compounds

• Tandem Mass Spectrometry 74%
• Uracil 71%
• Oligomer 70%
• High-Pressure Liquid Chromatography 67%
• Oxidative Stress 44%
• Nucleobase 24%
• Double-Stranded DNA 23%
• Single-Stranded DNA 23%
• Electrospray Ionization 20%
• Label 19%
• Indicator 19%
• Mutation 18%
• Ionization 17%
• Heat 16%
• Adduct 15%
• Aldehyde 15%
• Mass Spectrometry 14%
• Probe 13%
• Molecule 7%