Do stem cells exist in the adult kidney?

Sandeep Gupta, Mark E. Rosenberg

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations

Abstract

Adult stem cells exist in many organs and play a critical role in normal cell turnover and the response to injury. The existence of adult stem cells in the mammalian kidney remains controversial. Kidney stem cells have been isolated and characterized by many groups, often with discrepant results. This article will review the current state of knowledge regarding adult kidney stem cells and discuss future directions for kidney stem cell research.

Original languageEnglish (US)
Pages (from-to)607-613
Number of pages7
JournalAmerican Journal of Nephrology
Volume28
Issue number4
DOIs
StatePublished - Jun 2008

Keywords

  • Acute renal failure
  • Oct-4 stem cell marker
  • Progenitor cells
  • Sca-1 stem cell marker
  • Stem cells, regeneration

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