TY - JOUR
T1 - Endoscopic ultrasound-guided fine-needle aspiration findings of gastrointestinal leiomyomas and gastrointestinal stromal tumors
AU - Stelow, Edward B.
AU - Stanley, Michael W.
AU - Mallery, Shawn
AU - Lai, Rebecca
AU - Linzie, Bradley M.
AU - Bardales, Ricardo H.
PY - 2003/5/1
Y1 - 2003/5/1
N2 - True leiomyomas of the gastrointestinal system are rare but remain the most common mesenchymal tumors of the esophagus. It has become important to distinguish these tumors from gastrointestinal stromal tumors (GISTS) because the neoplasms have different prognoses and treatment options. We describe and compare clinical findings and the following fine-needle aspiration (FNA) features of 9 gastrointestinal leiomyomas and 19 GISTs sampled with endoscopic ultrasound: overall cellularity, cell group features, cell shape and cytoplasmic features, nuclear characteristics, background, cell block features. and immunohistochemical results. Gastrointestinal leiomyomas and GISTs have different clinical and cytologic features that help pathologists distinguish these tumors, and the immunohistochemical findings that help define these lesions can be derived readily from cell block material obtained by endoscopic ultrasound-guided FNA.
AB - True leiomyomas of the gastrointestinal system are rare but remain the most common mesenchymal tumors of the esophagus. It has become important to distinguish these tumors from gastrointestinal stromal tumors (GISTS) because the neoplasms have different prognoses and treatment options. We describe and compare clinical findings and the following fine-needle aspiration (FNA) features of 9 gastrointestinal leiomyomas and 19 GISTs sampled with endoscopic ultrasound: overall cellularity, cell group features, cell shape and cytoplasmic features, nuclear characteristics, background, cell block features. and immunohistochemical results. Gastrointestinal leiomyomas and GISTs have different clinical and cytologic features that help pathologists distinguish these tumors, and the immunohistochemical findings that help define these lesions can be derived readily from cell block material obtained by endoscopic ultrasound-guided FNA.
KW - Endoscopic ultrasound
KW - Fine-needle aspiration
KW - Gastrointestinal stromal tumor
KW - Immunohistochemistry
KW - Leiomyoma
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U2 - 10.1309/UWUVQ0010D9W0HPN
DO - 10.1309/UWUVQ0010D9W0HPN
M3 - Article
C2 - 12760289
SN - 0002-9173
VL - 119
SP - 703
EP - 708
JO - American Journal of Clinical Pathology
JF - American Journal of Clinical Pathology
IS - 5
ER -