Evidence for the replication of bovine leukemia virus in the B lymphocytes.

P. S. Paul; K. A. Pomeroy; D. W. Johnson; C. C. Muscoplat; B. S. Handwerger; F. F. Soper; D. K. Sorensen

Evidence for the replication of bovine leukemia virus in the B lymphocytes.

P. S. Paul, K. A. Pomeroy, D. W. Johnson, C. C. Muscoplat, B. S. Handwerger, F. F. Soper, D. K. Sorensen

Administration (CFANS)

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Abstract

Bovine peripheral blood lymphocytes from a cow with persistent lymphocytosis were separated on nylon wool columns into nylon-adherent and nonadherent populations. Nylon-adherent cells were highly enriched for surface immunoglobulin (SIg) bearing B lymphocytes (95.5%) and nonadherent cells for SIg negative non-B cells, presumably T lymphocytes (96.3%). The B lymphocytes were found to be the major producers for bovine leukemia virus. A total of 39% of the B-enriched cells, surviving after 72 hours in culture, produced bovine leukemia virus as compared with 0.5% of the non-B cells.

Original language	English (US)
Pages (from-to)	873-876
Number of pages	4
Journal	American journal of veterinary research
Volume	38
Issue number	6
State	Published - Jun 1 1977

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

OpenUrl availability

Full text

Cite this

@article{115e8f8d54a84f44a93e499e2bc0ac33,

title = "Evidence for the replication of bovine leukemia virus in the B lymphocytes.",

abstract = "Bovine peripheral blood lymphocytes from a cow with persistent lymphocytosis were separated on nylon wool columns into nylon-adherent and nonadherent populations. Nylon-adherent cells were highly enriched for surface immunoglobulin (SIg) bearing B lymphocytes (95.5%) and nonadherent cells for SIg negative non-B cells, presumably T lymphocytes (96.3%). The B lymphocytes were found to be the major producers for bovine leukemia virus. A total of 39% of the B-enriched cells, surviving after 72 hours in culture, produced bovine leukemia virus as compared with 0.5% of the non-B cells.",

author = "Paul, {P. S.} and Pomeroy, {K. A.} and Johnson, {D. W.} and Muscoplat, {C. C.} and Handwerger, {B. S.} and Soper, {F. F.} and Sorensen, {D. K.}",

year = "1977",

month = jun,

day = "1",

language = "English (US)",

volume = "38",

pages = "873--876",

journal = "American journal of veterinary research",

issn = "0002-9645",

publisher = "American Veterinary Medical Association",

number = "6",

}

TY - JOUR

T1 - Evidence for the replication of bovine leukemia virus in the B lymphocytes.

AU - Paul, P. S.

AU - Pomeroy, K. A.

AU - Johnson, D. W.

AU - Muscoplat, C. C.

AU - Handwerger, B. S.

AU - Soper, F. F.

AU - Sorensen, D. K.

PY - 1977/6/1

Y1 - 1977/6/1

N2 - Bovine peripheral blood lymphocytes from a cow with persistent lymphocytosis were separated on nylon wool columns into nylon-adherent and nonadherent populations. Nylon-adherent cells were highly enriched for surface immunoglobulin (SIg) bearing B lymphocytes (95.5%) and nonadherent cells for SIg negative non-B cells, presumably T lymphocytes (96.3%). The B lymphocytes were found to be the major producers for bovine leukemia virus. A total of 39% of the B-enriched cells, surviving after 72 hours in culture, produced bovine leukemia virus as compared with 0.5% of the non-B cells.

AB - Bovine peripheral blood lymphocytes from a cow with persistent lymphocytosis were separated on nylon wool columns into nylon-adherent and nonadherent populations. Nylon-adherent cells were highly enriched for surface immunoglobulin (SIg) bearing B lymphocytes (95.5%) and nonadherent cells for SIg negative non-B cells, presumably T lymphocytes (96.3%). The B lymphocytes were found to be the major producers for bovine leukemia virus. A total of 39% of the B-enriched cells, surviving after 72 hours in culture, produced bovine leukemia virus as compared with 0.5% of the non-B cells.

UR - http://www.scopus.com/inward/record.url?scp=0017503912&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017503912&partnerID=8YFLogxK

M3 - Article

C2 - 195501

AN - SCOPUS:0017503912

SN - 0002-9645

VL - 38

SP - 873

EP - 876

JO - American journal of veterinary research

JF - American journal of veterinary research

IS - 6

ER -

Evidence for the replication of bovine leukemia virus in the B lymphocytes.

Abstract

UN SDGs

OpenUrl availability

Other files and links

Fingerprint

Cite this