Abstract
Exercise activates adrenergic and purinergic pathways that regulate activity of ion channels on airway epithelia cells and sweat glands. Therefore, we hypothesize that exercise is not only an important therapy for cystic fibrosis (CF) patients by facilitating systemic improvements but, more importantly, that exercise can improve the pathophysiological ion dysregulation at a cellular level, thereby enhancing quality of life in CF.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 155-160 |
| Number of pages | 6 |
| Journal | Exercise and sport sciences reviews |
| Volume | 39 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jul 2011 |
| Externally published | Yes |
Keywords
- ADBR2
- CFTR
- ENaC
- P2Y2
- airway surface liquid
- sweat gland
- thermoregulation
