Experimental and theoretical investigation of cubic FeCo nanoparticles for magnetic hyperthermia

Ying Jing; Hweerin Sohn; Timothy Kline; Randall H. Victora; Jian Ping Wang

doi:10.1063/1.3074136

Experimental and theoretical investigation of cubic FeCo nanoparticles for magnetic hyperthermia

Ying Jing, Hweerin Sohn, Timothy Kline, Randall H. Victora, Jian Ping Wang

Electrical and Computer Engineering

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Abstract

Magnetic nanoparticles have great potential as heating elements for use in magnetic hyperthermia for cancer therapy and drug release. A problem with widely used magnetite and mag-hematite nanoparticles is the relatively low magnetization, which results in low heating efficiency. Here high-magnetic-moment Fe70 Co30 nanoparticles with a cubic shape were synthesized using a gas condensation sputtering technique for potential magnetic hyperthermia application. The mean size of nanoparticles was 12 nm with 13.6% standard deviation. Micromagnetic simulation of particles' experimental hysteresis loop suggests that their behavior is dominated by a uniaxial anisotropy.

Original language	English (US)
Article number	07B305
Journal	Journal of Applied Physics
Volume	105
Issue number	7
DOIs	https://doi.org/10.1063/1.3074136
State	Published - 2009

Bibliographical note

Funding Information:
This work was partially supported by the Medical Device Center of Institute of Engineering in Medicine at University of Minnesota and National Science Foundation Contract No. BME 0730825. Parts of this work were carried out in the Minnesota Characterization Facility which receives partial support from NSF through the NNIN program.

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title = "Experimental and theoretical investigation of cubic FeCo nanoparticles for magnetic hyperthermia",

abstract = "Magnetic nanoparticles have great potential as heating elements for use in magnetic hyperthermia for cancer therapy and drug release. A problem with widely used magnetite and mag-hematite nanoparticles is the relatively low magnetization, which results in low heating efficiency. Here high-magnetic-moment Fe70 Co30 nanoparticles with a cubic shape were synthesized using a gas condensation sputtering technique for potential magnetic hyperthermia application. The mean size of nanoparticles was 12 nm with 13.6% standard deviation. Micromagnetic simulation of particles' experimental hysteresis loop suggests that their behavior is dominated by a uniaxial anisotropy.",

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year = "2009",

doi = "10.1063/1.3074136",

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AU - Kline, Timothy

AU - Victora, Randall H.

AU - Wang, Jian Ping

N1 - Funding Information: This work was partially supported by the Medical Device Center of Institute of Engineering in Medicine at University of Minnesota and National Science Foundation Contract No. BME 0730825. Parts of this work were carried out in the Minnesota Characterization Facility which receives partial support from NSF through the NNIN program.

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Y1 - 2009

N2 - Magnetic nanoparticles have great potential as heating elements for use in magnetic hyperthermia for cancer therapy and drug release. A problem with widely used magnetite and mag-hematite nanoparticles is the relatively low magnetization, which results in low heating efficiency. Here high-magnetic-moment Fe70 Co30 nanoparticles with a cubic shape were synthesized using a gas condensation sputtering technique for potential magnetic hyperthermia application. The mean size of nanoparticles was 12 nm with 13.6% standard deviation. Micromagnetic simulation of particles' experimental hysteresis loop suggests that their behavior is dominated by a uniaxial anisotropy.

AB - Magnetic nanoparticles have great potential as heating elements for use in magnetic hyperthermia for cancer therapy and drug release. A problem with widely used magnetite and mag-hematite nanoparticles is the relatively low magnetization, which results in low heating efficiency. Here high-magnetic-moment Fe70 Co30 nanoparticles with a cubic shape were synthesized using a gas condensation sputtering technique for potential magnetic hyperthermia application. The mean size of nanoparticles was 12 nm with 13.6% standard deviation. Micromagnetic simulation of particles' experimental hysteresis loop suggests that their behavior is dominated by a uniaxial anisotropy.

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Experimental and theoretical investigation of cubic FeCo nanoparticles for magnetic hyperthermia

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