Fatal Complement-Induced Leukostasis After Diatrizoate Injection: Principles of Clinicopathologic Diagnosis

Henry Schneiderman; Dale E. Hammerschmidt; Anne Ritke McCall; Harry S. Jacob

doi:10.1001/jama.1983.03340170066031

Fatal Complement-Induced Leukostasis After Diatrizoate Injection: Principles of Clinicopathologic Diagnosis

Henry Schneiderman, Dale E. Hammerschmidt, Anne Ritke McCall, Harry S. Jacob

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

A case of fatal radiographic contrast medium (RCM)-induced pulmonary granulocyte aggregation (leukostasis) showed massive elevation of the postmortem histamine level. Suspicion of this phenomenon in diverse clinical settings permits clinical and pathological documentation via increased plasma levels of C3a and other means. The existence of effective prophylaxis stimulates a search for predictive tests.

Original language	English (US)
Pages (from-to)	2340-2342
Number of pages	3
Journal	JAMA: The Journal of the American Medical Association
Volume	250
Issue number	17
DOIs	https://doi.org/10.1001/jama.1983.03340170066031
State	Published - Nov 4 1983
Externally published	Yes

Access

10.1001/jama.1983.03340170066031

OpenUrl availability

Full text

Cite this

@article{29d5f873af47408aac31d267b025d5c2,

title = "Fatal Complement-Induced Leukostasis After Diatrizoate Injection: Principles of Clinicopathologic Diagnosis",

abstract = "A case of fatal radiographic contrast medium (RCM)-induced pulmonary granulocyte aggregation (leukostasis) showed massive elevation of the postmortem histamine level. Suspicion of this phenomenon in diverse clinical settings permits clinical and pathological documentation via increased plasma levels of C3a and other means. The existence of effective prophylaxis stimulates a search for predictive tests.",

author = "Henry Schneiderman and Hammerschmidt, {Dale E.} and McCall, {Anne Ritke} and Jacob, {Harry S.}",

year = "1983",

month = nov,

day = "4",

doi = "10.1001/jama.1983.03340170066031",

language = "English (US)",

volume = "250",

pages = "2340--2342",

journal = "JAMA: The Journal of the American Medical Association",

issn = "0098-7484",

publisher = "American Medical Association",

number = "17",

}

TY - JOUR

T1 - Fatal Complement-Induced Leukostasis After Diatrizoate Injection

T2 - Principles of Clinicopathologic Diagnosis

AU - Schneiderman, Henry

AU - Hammerschmidt, Dale E.

AU - McCall, Anne Ritke

AU - Jacob, Harry S.

PY - 1983/11/4

Y1 - 1983/11/4

N2 - A case of fatal radiographic contrast medium (RCM)-induced pulmonary granulocyte aggregation (leukostasis) showed massive elevation of the postmortem histamine level. Suspicion of this phenomenon in diverse clinical settings permits clinical and pathological documentation via increased plasma levels of C3a and other means. The existence of effective prophylaxis stimulates a search for predictive tests.

AB - A case of fatal radiographic contrast medium (RCM)-induced pulmonary granulocyte aggregation (leukostasis) showed massive elevation of the postmortem histamine level. Suspicion of this phenomenon in diverse clinical settings permits clinical and pathological documentation via increased plasma levels of C3a and other means. The existence of effective prophylaxis stimulates a search for predictive tests.

UR - http://www.scopus.com/inward/record.url?scp=0020514212&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020514212&partnerID=8YFLogxK

U2 - 10.1001/jama.1983.03340170066031

DO - 10.1001/jama.1983.03340170066031

M3 - Article

C2 - 6195360

AN - SCOPUS:0020514212

SN - 0098-7484

VL - 250

SP - 2340

EP - 2342

JO - JAMA: The Journal of the American Medical Association

JF - JAMA: The Journal of the American Medical Association

IS - 17

ER -

Fatal Complement-Induced Leukostasis After Diatrizoate Injection: Principles of Clinicopathologic Diagnosis

Abstract

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this