Orexin A and orexin B were microinjected into the perifornical hypothalamus (PFH), lateral hypothalamus (LH), hypothalamic paraventricular nucleus (PVN), and ventral tegmental area (VTA) of male Sprague-Dawley rats. Orexin B (15 nmol) was also injected into the lateral cerebral ventricle (i.c,v.). Orexin A (≥ 500 pmol) stimulated feeding in the PFH and LH, but not in the VTA or PVN. Orexin B stimulated feeding only when injected i.c.v.
Bibliographical noteFunding Information:
This work was supported by funds from the Minnesota Obesity Center (P30 DK-50456).
- Feeding behavior
- Hypothalamic area, lateral
- Hypothalamic area, perifornical