Fibronectin in Foreign Body-Induced Sarcomas and Preneoplastic Cells

Gwen C. Macdonald, Leo T Furcht, K. Gerhard Brand

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Foreign body (FB)-induced murine sarcoma cells and advanced preneoplastic cells as well as normal fibroblasts produce fibronectin (FN) in primary culture; cells at early preneoplasia do not. Hence, the neoplastic properties of FB-induced sarcomas do not depend on absence of FN. Temporary FN repression during early preneoplasia is associated with certain phenotypic cell characteristics.

Original languageEnglish (US)
Pages (from-to)89-92
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Issue number1
StatePublished - Jan 1983

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