TY - JOUR
T1 - Habitual sleep patterns and risk for stroke and coronary heart disease
T2 - A 10-year follow-up from NHANES I
AU - Qureshi, Adnan I.
AU - Giles, Wayne H.
AU - Croft, Janet B.
AU - Bliwise, Donald L.
PY - 1997/4
Y1 - 1997/4
N2 - Background: Habitual sleep patterns may independently affect morbidity and mortality. However, the effect of habitual sleep patterns on the risk for stroke and coronary heart disease is unclear. Methods: We evaluated the association between sleep duration and daytime somnolence (often or almost always taking daytime naps) with the incidence of stroke and coronary heart disease in a national cohort of 7,844 adults who participated in the First National Health and Nutrition Examination Survey Epidemiologic Follow-up Study. Cox proportional hazards analyses were used to examine these relationships during the 10-year follow-up. Results: After adjusting for differences in age, race, gender, education, cigarette smoking, body mass index, serum cholesterol, systolic blood pressure, and diabetes mellitus, the risk for stroke was increased in persons who reported sleeping greater than 8 hours at night compared with persons who slept between 6 and 8 hours (relative risk [RR] = 1.5, 95% confidence interval [CI] 1.1 to 2.0). Daytime somnolence was also associated with stroke incidence (RR = 1.4, 95% CI = 1.1 to 1.8). Persons who reported both greater than 8 hours of sleep and daytime somnolence were at the greatest risk for stroke (RR = 1.9, 95% CI = 1.2 to 3.1). Similar results were also found for coronary heart disease, although the results did not reach statistical significance in the multivariate adjusted model. Conclusions: Habitual sleep patterns have significant effects on the risk for stroke.
AB - Background: Habitual sleep patterns may independently affect morbidity and mortality. However, the effect of habitual sleep patterns on the risk for stroke and coronary heart disease is unclear. Methods: We evaluated the association between sleep duration and daytime somnolence (often or almost always taking daytime naps) with the incidence of stroke and coronary heart disease in a national cohort of 7,844 adults who participated in the First National Health and Nutrition Examination Survey Epidemiologic Follow-up Study. Cox proportional hazards analyses were used to examine these relationships during the 10-year follow-up. Results: After adjusting for differences in age, race, gender, education, cigarette smoking, body mass index, serum cholesterol, systolic blood pressure, and diabetes mellitus, the risk for stroke was increased in persons who reported sleeping greater than 8 hours at night compared with persons who slept between 6 and 8 hours (relative risk [RR] = 1.5, 95% confidence interval [CI] 1.1 to 2.0). Daytime somnolence was also associated with stroke incidence (RR = 1.4, 95% CI = 1.1 to 1.8). Persons who reported both greater than 8 hours of sleep and daytime somnolence were at the greatest risk for stroke (RR = 1.9, 95% CI = 1.2 to 3.1). Similar results were also found for coronary heart disease, although the results did not reach statistical significance in the multivariate adjusted model. Conclusions: Habitual sleep patterns have significant effects on the risk for stroke.
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U2 - 10.1212/wnl.48.4.904
DO - 10.1212/wnl.48.4.904
M3 - Article
C2 - 9109875
AN - SCOPUS:0030975393
SN - 0028-3878
VL - 48
SP - 904
EP - 911
JO - Neurology
JF - Neurology
IS - 4
ER -