Heme oxygenase-1 gene delivery by Sleeping Beauty inhibits vascular stasis in a murine model of sickle cell disease

Medicine & Life Sciences

• Beauty 100%
• Heme Oxygenase-1 86%
• Sickle Cell Anemia 80%
• Blood Vessels 43%
• Transgenes 33%
• Genes 29%
• Heme 27%
• Biliverdine 25%
• Liver 16%
• Carbon Monoxide 16%
• Transposases 11%
• Hemin 11%
• DNA Transposable Elements 10%
• Hydrodynamics 9%
• Vascular Cell Adhesion Molecule-1 9%
• Injections 9%
• Skin 9%
• NF-kappa B 8%
• p38 Mitogen-Activated Protein Kinases 8%
• Restriction Fragment Length Polymorphisms 8%
• Bilirubin 8%
• Tail 7%
• Albumins 7%
• Hepatocytes 6%
• Veins 6%
• Plasmids 6%
• Real-Time Polymerase Chain Reaction 6%
• Hypoxia 6%
• Anti-Inflammatory Agents 6%
• Immunohistochemistry 5%
• Staining and Labeling 5%
• Inflammation 4%
• Messenger RNA 4%
• Enzymes 4%
• Serum 3%
• Proteins 3%

Chemical Compounds

• Heme 68%
• Biliverdin 23%
• Degradation Product 15%
• Cytoprotective 11%
• Messenger RNA 10%
• Bilirubin 9%
• Chain Reaction 8%
• Antiinflammatory 7%
• Hydrodynamics 7%
• Protective 6%
• Protein 6%
• Enzyme Activity 6%
• Length 4%