High-sensitivity cardiac troponin assays and unstable angina

Yader Sandoval; Fred S. Apple; Stephen W. Smith

doi:10.1177/2048872616658591

High-sensitivity cardiac troponin assays and unstable angina

Yader Sandoval, Fred S. Apple, Stephen W. Smith

Research output: Contribution to journal › Review article › peer-review

41 Scopus citations

Abstract

The term unstable angina has been conventionally applied to patients with myocardial ischemia without myocardial necrosis. However, while the clinical context has remained constant over time, the biomarkers of myocardial injury and acute myocardial infarction have evolved. High-sensitivity cardiac troponin assays have several key analytical differences from prior cardiac troponin assay generations, which may alter the diagnosis and frequency of unstable angina, as well as affect our understanding of previously developed risk stratification strategies. This document reviews the current challenges in regards to unstable angina when using high-sensitivity cardiac troponin I and T assays.

Original language	English (US)
Pages (from-to)	120-128
Number of pages	9
Journal	European heart journal. Acute cardiovascular care
Volume	7
Issue number	2
DOIs	https://doi.org/10.1177/2048872616658591
State	Published - Mar 1 2018
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2016, © The European Society of Cardiology 2016.

Keywords

acute coronary syndrome
cardiac troponin
high-sensitivity cardiac troponin
myocardial infarction
Unstable angina

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KW - Unstable angina

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High-sensitivity cardiac troponin assays and unstable angina

Abstract

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