Hippocampus in autism: A Golgi analysis

Gerald V. Raymond; Margaret L. Bauman; Thomas L. Kemper

doi:10.1007/s004010050401

Hippocampus in autism: A Golgi analysis

Gerald V. Raymond, Margaret L. Bauman, Thomas L. Kemper

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Abstract

Autism is a behaviorally defined syndrome in which neuropathological abnormalities have been identified in the limbic system and cerebellum. The morphology of hippocampal neurons in two cases of infantile autism was studied and compared to age-matched controls. CA4 neurons in autistic children were smaller in perikaryon area and dendritic branching of both CA4 and CA1 neurons was less than in controls. These findings are consistent with previous studies and suggest a curtailment in maturation in the pathogenesis of autism.

Original language	English (US)
Pages (from-to)	117-119
Number of pages	3
Journal	Acta Neuropathologica
Volume	91
Issue number	1
DOIs	https://doi.org/10.1007/s004010050401
State	Published - 1996
Externally published	Yes

Keywords

Autism
Hippocampus

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abstract = "Autism is a behaviorally defined syndrome in which neuropathological abnormalities have been identified in the limbic system and cerebellum. The morphology of hippocampal neurons in two cases of infantile autism was studied and compared to age-matched controls. CA4 neurons in autistic children were smaller in perikaryon area and dendritic branching of both CA4 and CA1 neurons was less than in controls. These findings are consistent with previous studies and suggest a curtailment in maturation in the pathogenesis of autism.",

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AU - Bauman, Margaret L.

AU - Kemper, Thomas L.

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AB - Autism is a behaviorally defined syndrome in which neuropathological abnormalities have been identified in the limbic system and cerebellum. The morphology of hippocampal neurons in two cases of infantile autism was studied and compared to age-matched controls. CA4 neurons in autistic children were smaller in perikaryon area and dendritic branching of both CA4 and CA1 neurons was less than in controls. These findings are consistent with previous studies and suggest a curtailment in maturation in the pathogenesis of autism.

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Hippocampus in autism: A Golgi analysis

Abstract

Keywords

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