Hysteresis in the glucose permeability versus pH characteristic for a responsive hydrogel membrane

John P. Baker, Ronald A. Siegel

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

A side-by-side diffusion cell was used to study the permeability of glucose through a temperature- and pH-sensitive poly(N-isopropylacrylamide-co-methacrylic acid) hydrogel membrane. At fixed temperature (37°C), lowering pH in one side of the cell induced hydrogel volume collapse and strongly attenuated glucose permeation across the membrane. Hysteresis was observed in the glucose permeability versus pH characteristic.

Original languageEnglish (US)
Pages (from-to)409-415
Number of pages7
JournalMacromolecular Rapid Communications
Volume17
Issue number6
DOIs
StatePublished - Jun 1996

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