Abstract
In Candida albicans, calcineurin mediates tolerance to azole antifungal drugs, survival in serum, and virulence. In this study, we examined 24 Candida isolates from liver transplant recipients receiving a calcineurin inhibitor as a component of their immunosuppressive therapy. We were unable to detect a difference in susceptibility to calcineurin inhibitors in combination with fluconazole, serum, or calcium in these isolates.
Original language | English (US) |
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Pages (from-to) | 1573-1577 |
Number of pages | 5 |
Journal | Antimicrobial agents and chemotherapy |
Volume | 50 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2006 |