TY - JOUR
T1 - Impact of a thrombolysis research trial on time to treatment for acute myocardial infarction in the emergency department
AU - Boisjolie, Charlene R.
AU - Sharkey, Scott W.
AU - Cannon, Christopher P.
AU - Brunette, Doug
AU - Haugland, J. Mark
AU - Thatcher, Jackson L.
AU - Henry, Timothy D.
PY - 1995/8/15
Y1 - 1995/8/15
N2 - Because time to treatment in AMI is a critical factor in long-term outcome, it is important that complex trials designed to improve reperfusion therapy do not delay the time to treatment. Participation in the TIMI 5 trial did not significantly prolong our door-to-needle time. These results indicate that, if done carefully, complex, labor-intensive studies can be performed within a reasonable time limit. Care should be taken to design protocols incorporating easy drug preparation, informed consent by the ED, and efficiency of trial initiation.
AB - Because time to treatment in AMI is a critical factor in long-term outcome, it is important that complex trials designed to improve reperfusion therapy do not delay the time to treatment. Participation in the TIMI 5 trial did not significantly prolong our door-to-needle time. These results indicate that, if done carefully, complex, labor-intensive studies can be performed within a reasonable time limit. Care should be taken to design protocols incorporating easy drug preparation, informed consent by the ED, and efficiency of trial initiation.
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U2 - 10.1016/S0002-9149(99)80108-8
DO - 10.1016/S0002-9149(99)80108-8
M3 - Article
C2 - 7639167
AN - SCOPUS:0029119573
SN - 0002-9149
VL - 76
SP - 396
EP - 398
JO - The American Journal of Cardiology
JF - The American Journal of Cardiology
IS - 5
ER -