Impact of a thrombolysis research trial on time to treatment for acute myocardial infarction in the emergency department

Charlene R. Boisjolie, Scott W. Sharkey, Christopher P. Cannon, Doug Brunette, J. Mark Haugland, Jackson L. Thatcher, Timothy D. Henry

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Because time to treatment in AMI is a critical factor in long-term outcome, it is important that complex trials designed to improve reperfusion therapy do not delay the time to treatment. Participation in the TIMI 5 trial did not significantly prolong our door-to-needle time. These results indicate that, if done carefully, complex, labor-intensive studies can be performed within a reasonable time limit. Care should be taken to design protocols incorporating easy drug preparation, informed consent by the ED, and efficiency of trial initiation.

Original languageEnglish (US)
Pages (from-to)396-398
Number of pages3
JournalThe American Journal of Cardiology
Volume76
Issue number5
DOIs
StatePublished - Aug 15 1995

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