Impact of different coils on biochemical T2 and T2*relaxation time mapping of articular patella cartilage

Milena L. Pachowsky, Siegfried Trattnig, Sebastian Apprich, Andreas Mauerer, Stephan Zbyn, Goetz H. Welsch

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Objective: The purpose of our study was to assess T2 and T2*relaxation time values of patella cartilage in healthy volunteers using three different coils at 3.0 Tesla MRI and their influence on the quantitative values. Methods: Fifteen volunteers were examined on the same 3-Tesla MR unit using three different coils: (i) a dedicated eight-channel knee phased-array coil; (ii) an eight-channel multi-purpose coil, and (iii) a one-channel 1H surface coil. T2 and T2*relaxation time measurements were prepared by a multi-echo spinecho respectively a gradient-echo sequence. A semi-automatic region-of-interest analysis was performed for patella cartilage. To allow stratification, a subregional analysis was carried out (deep-superficial cartilage layer). Statistical analysis-of-variance was performed. Results: The mean quantitative T2 values showed statistically significant differences in all comparison combinations. The differences between the mean quantitative T2*values were slightly less pronounced than the T2 evaluation and only the comparison between (i) and (ii) showed a significant difference. The results of T2 and T2*values showed, independent of the used coil, higher values in the superficial zone compared to the deep zone (p < 0.05). Looking at the signal alterations, all coils showed clearly higher values (and thus more signal alterations as a sign of noise) in the deep layer. The validation of the reliability showed a high intra-class correlation coefficient and hence a very high plausibility (ICC was between 0.870 and 0.905 for T2 mapping and between 0.879 and 0.888 for T2*mapping). Conclusions: The present results demonstrate that biochemical T2 and T2*mapping is significantly dependent on the utilized coil.

Original languageEnglish (US)
Pages (from-to)1565-1572
Number of pages8
JournalSkeletal Radiology
Volume42
Issue number11
DOIs
StatePublished - Nov 2013
Externally publishedYes

Bibliographical note

Funding Information:
Acknowledgements Support for this study was provided by the German Research Fondation (DFG) - DACH Grant WE 4881/1 "Multi-parametric visualization of knee joint ultra-structure: Validation of biochemical magnetic resonance imaging from bench to bedside".

Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.

Keywords

  • Cartilage
  • Coil
  • MRI
  • T2
  • T2 mapping
  • mapping

Fingerprint Dive into the research topics of 'Impact of different coils on biochemical T2 and T2*relaxation time mapping of articular patella cartilage'. Together they form a unique fingerprint.

Cite this