In vitro and in vivo evaluation of biodegradable embolic microspheres with tunable anticancer drug release

Medicine & Life Sciences

• Microspheres 77%
• Drug Liberation 73%
• In Vitro Techniques 33%
• Carboxymethylcellulose Sodium 24%
• Arteries 21%
• Chitosan 20%
• Polymers 16%
• Schiff Bases 13%
• Human Umbilical Vein Endothelial Cells 10%
• Coculture Techniques 9%
• Polysaccharides 8%
• Doxorubicin 8%
• Rabbits 6%
• Water 6%
• Enzymes 5%
• Kidney 5%
• Pharmaceutical Preparations 3%
• Therapeutics 1%

Engineering & Materials Science

• Microspheres 100%
• Chitosan 26%
• Cellulose 20%
• Natural polymers 15%
• Endothelial cells 13%
• Polysaccharides 13%
• Degradation 13%
• Monolayers 12%
• Cell culture 12%
• Biocompatibility 11%
• Enzymes 10%
• Swelling 10%
• Polymers 6%
• Water 5%

Chemical Compounds

• Microsphere 64%
• Drug 39%
• Biodegradability 19%
• Chitosan 15%
• Doxorubicin 9%
• Size Distribution 8%
• Polysaccharide 8%
• Schiff Base 7%
• Monolayer 7%
• Cleavage 6%
• Application 5%
• Modification 5%
• Time 3%