TY - JOUR
T1 - In vivo comparison of fourier-domain optical coherence tomography and intravascular ultrasonography
AU - Ramesh, Sathyadeepak
AU - Papayannis, Aristotelis
AU - Abdel-Karim, Abdul Rahman
AU - Banerjee, Subhash
AU - Brilakis, Emmanouil
PY - 2012/3
Y1 - 2012/3
N2 - BACKGROUND: We sought to evaluate the findings of Fourier-domain optical coherence tomography (FD-OCT) and intravascular ultrasonography (IVUS) used for the in vivo assessment of coronary lesions. METHODS: We identified 19 lesions in 15 patients undergoing percutaneous coronary intervention that were assessed by both FD-OCT and IVUS and compared the lumen area and maximum/minimum lumen diameter at the site of maximum stenosis and the proximal and distal reference cross-sections. RESULTS: At the site of maximum stenosis, excellent correlation was found between FD-OCT and IVUS measurements: minimum lumen area (3.80 ± 2.36 mm 2 and 4.60 ± 2.13 mm 2, respectively; P=.002; Spearman's = 0.94), maximum lumen diameter (2.30 ± 0.79 mm 2 and 2.54 ± 0.60 mm 2, respectively; P=.005; Spearman's = 0.93), and minimum lumen diameter (1.89 ± 0.69 mm 2 and 2.24 ± 0.54 mm 2, respectively; P=.0001; Spearman's = 0.90). Weaker correlations were found between FD-OCT and IVUS measurements of the proximal reference lumen area (4.74 ± 1.86 mm 2 and 5.16 ± 2.10 mm 2, respectively; P=.33; Spearman's = 0.76) and distal reference lumen area (5.14 ± 1.60 mm 2 and 5.47 ± 2.45 mm 2, respectively; P=.144; Spearman's = 0.72). CONCLUSIONS: Excellent correlation was found in FD-OCT and IVUS luminal measurements at the site of maximum coronary stenosis with weaker correlation at the proximal and distal reference cross-sections. FD-OCT minimum lumen area measurements were smaller than the IVUS measurements.
AB - BACKGROUND: We sought to evaluate the findings of Fourier-domain optical coherence tomography (FD-OCT) and intravascular ultrasonography (IVUS) used for the in vivo assessment of coronary lesions. METHODS: We identified 19 lesions in 15 patients undergoing percutaneous coronary intervention that were assessed by both FD-OCT and IVUS and compared the lumen area and maximum/minimum lumen diameter at the site of maximum stenosis and the proximal and distal reference cross-sections. RESULTS: At the site of maximum stenosis, excellent correlation was found between FD-OCT and IVUS measurements: minimum lumen area (3.80 ± 2.36 mm 2 and 4.60 ± 2.13 mm 2, respectively; P=.002; Spearman's = 0.94), maximum lumen diameter (2.30 ± 0.79 mm 2 and 2.54 ± 0.60 mm 2, respectively; P=.005; Spearman's = 0.93), and minimum lumen diameter (1.89 ± 0.69 mm 2 and 2.24 ± 0.54 mm 2, respectively; P=.0001; Spearman's = 0.90). Weaker correlations were found between FD-OCT and IVUS measurements of the proximal reference lumen area (4.74 ± 1.86 mm 2 and 5.16 ± 2.10 mm 2, respectively; P=.33; Spearman's = 0.76) and distal reference lumen area (5.14 ± 1.60 mm 2 and 5.47 ± 2.45 mm 2, respectively; P=.144; Spearman's = 0.72). CONCLUSIONS: Excellent correlation was found in FD-OCT and IVUS luminal measurements at the site of maximum coronary stenosis with weaker correlation at the proximal and distal reference cross-sections. FD-OCT minimum lumen area measurements were smaller than the IVUS measurements.
KW - coronary angiography
KW - intravascular ultrasonography
KW - optical coherence tomography
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M3 - Article
C2 - 22388302
AN - SCOPUS:84858374020
SN - 1042-3931
VL - 24
SP - 111
EP - 115
JO - Journal of Invasive Cardiology
JF - Journal of Invasive Cardiology
IS - 3
ER -