In vivo NMR investigations of glyphosate influences on plant metabolism

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Glyphosate is the world's most widely used herbicide; popular due to its relative low cost, low toxicity, and high efficacy in controlling most common weed species. Genetic engineering of crop seeds to be glyphosate-tolerant has facilitated the modern global agricultural practice whereby both weeds and crops are treated with herbicide, while only the crops survive. However, due to extreme selective pressure, glyphosate-resistant (GR) weed species are now found with increasing frequency in nature, threatening the dominant weed management system used in large-scale agriculture across much of the globe. In vivo NMR studies of plants have facilitated the discovery and understanding of the glyphosate-resistance mechanism of the multi-continent, highly invasive weed species, GR horseweed Conyza canadensis (L.) Cronq. and GR ryegrass (Lolium spp.). This study exemplifies how in vivo NMR spectroscopy can be used to better understand herbicide-associated metabolic alterations observed in living plants, which poses a significant threat to modern agriculture as it is currently practiced.

Original languageEnglish (US)
Pages (from-to)59-72
Number of pages14
JournalJournal of Magnetic Resonance
StatePublished - Jul 2018


  • Glyphosate
  • Glyphosate resistance
  • In vivo NMR of plants
  • Vacuole sequestration

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review

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