Inactivation of a two-component signal transduction system, SaeRS, eliminates adherence and attenuates virulence of Staphylococcus aureus

Agriculture & Biology

• Staphylococcus aureus 100%
• signal transduction 99%
• epithelial cells 97%
• inactivation 93%
• virulence 91%
• fibrinogen 62%
• animal pathogens 60%
• apoptosis 51%
• adhesion 49%
• binding proteins 48%
• lungs 44%
• infection 44%
• bacterial adhesion 40%
• regulon 34%
• hemolysins 33%
• fibronectins 32%
• proteins 28%
• cells 26%
• complement 23%
• toxins 23%
• reverse transcriptase polymerase chain reaction 21%
• death 21%
• promoter regions 20%
• mutation 19%
• gene expression 17%
• mice 16%
• organisms 16%
• bacteria 15%
• genes 9%

Medicine & Life Sciences

• Virulence 98%
• Staphylococcus aureus 97%
• Signal Transduction 88%
• Epithelial Cells 80%
• Fibrinogen 54%
• Carrier Proteins 48%
• Infections 40%
• Bacterial Adhesion 38%
• Regulon 37%
• Hemolysin Proteins 36%
• Complement C3 35%
• Apoptosis 34%
• Proteins 31%
• Lung 30%
• Reverse Transcriptase Polymerase Chain Reaction 28%
• Protein Binding 28%
• Fibronectins 27%
• Real-Time Polymerase Chain Reaction 22%
• Up-Regulation 20%
• Bacteria 19%
• Gene Expression 16%
• Mutation 15%
• Animals 14%
• In Vitro Techniques 12%
• Genes 11%