Interweaving the strands: β-catenin, an HIV Co-receptor, and schwann cell tumors

David Largaespada; Nancy Ratner

doi:10.1016/j.ccr.2013.03.001

Interweaving the strands: β-catenin, an HIV Co-receptor, and schwann cell tumors

David Largaespada, Nancy Ratner

Pediatrics - Hematology

Research output: Contribution to journal › Short survey › peer-review

9 Scopus citations

Abstract

WNT/β-catenin signaling is critical to the development of many cancer types. A paper by Mo and colleagues in a recent issue of Cell shows that autocrine CXCL12/CXCR4 chemokine signaling activates β-catenin signaling in a rare peripheral nerve sarcoma. Together with the availability of small molecules targeting CXCR4, this finding suggests new avenues for cancer therapy.

Original language	English (US)
Pages (from-to)	269-271
Number of pages	3
Journal	Cancer Cell
Volume	23
Issue number	3
DOIs	https://doi.org/10.1016/j.ccr.2013.03.001
State	Published - Mar 18 2013

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abstract = "WNT/β-catenin signaling is critical to the development of many cancer types. A paper by Mo and colleagues in a recent issue of Cell shows that autocrine CXCL12/CXCR4 chemokine signaling activates β-catenin signaling in a rare peripheral nerve sarcoma. Together with the availability of small molecules targeting CXCR4, this finding suggests new avenues for cancer therapy.",

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Interweaving the strands: β-catenin, an HIV Co-receptor, and schwann cell tumors

Abstract

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