Ischemic cardiac complications following G-CSF

Peter M. Eckman, Stefan C. Bertog, Robert F. Wilson, Timothy D. Henry

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Granulocyte-colony stimulating factor (G-CSF) is commonly used in bone marrow transplant donors to increase the number of circulating progenitor cells. G-CSF has also been studied following myocardial infarction, but concern has been raised about the risks of G-CSF administration in patients with coronary artery disease. We present two cases of ischemic cardiac complications that are likely to be related to administration of G-CSF and provide a contemporary overview of the literature on the cardiovascular risks of G-CSF.

Original languageEnglish (US)
Pages (from-to)98-101
Number of pages4
JournalCatheterization and Cardiovascular Interventions
Volume76
Issue number1
DOIs
StatePublished - Jul 1 2010

Keywords

  • Coronary artery disease
  • Filgrastim/adverse effects
  • Inflammation
  • Myocardial infarction

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