Leukotriene B4 induces EMT and vimentin expression in PANC-1 pancreatic cancer cells: Involvement of BLT2 via ERK2 activation

Medicine & Life Sciences

• Leukotriene B4 86%
• Epithelial-Mesenchymal Transition 72%
• Vimentin 72%
• Pancreatic Neoplasms 66%
• Phosphotransferases 14%
• Gene Silencing 13%
• Cadherins 12%
• LY 255283 12%
• Neoplasms 8%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 7%
• Chemotactic Factors 7%
• Mitogen-Activated Protein Kinase Kinases 6%
• Keratins 6%
• Pancreatitis 6%
• Smoke 6%
• Tobacco Products 6%
• Transfection 5%
• Small Interfering RNA 5%
• Plasmids 5%
• Complementary DNA 5%
• Leukocytes 5%
• RNA 4%
• Phosphorylation 4%
• Western Blotting 4%
• Cell Line 3%
• Polymerase Chain Reaction 3%
• Mutation 3%

Chemical Compounds

• Leukotriene B4 100%
• Leukotriene 35%
• EC 2.7.12.2 (Mitogen-Activated Protein Kinase Kinase) Inhibitor 14%
• Chemoattractant 12%
• Silencing RNA 11%
• Smoke 9%
• Complementary DNA 9%
• Agonist 8%
• Antagonist 8%
• Mutation 7%