Levels of immunoreactive dynorphin in brain and pituitary of hyperthyroid and hypothyroid rats

John E. Morley; Michael K. Elson; Allen S. Levine; Rex B. Shafer

doi:10.1016/0014-2999(82)90381-8

Levels of immunoreactive dynorphin in brain and pituitary of hyperthyroid and hypothyroid rats

John E. Morley, Michael K. Elson, Allen S. Levine, Rex B. Shafer

Medicine - Administration

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Abstract

Dynorphin is a potent opioid peptide. Using a highly sensitive radioimmunoassay we have measured the levels of immunoreactive (ir) dynorphin in the cortex, hypothalamus, anterior and posterior pituitary in hyperthyroid and hypothyroid rats. Ir dynorphin levels were increased in the cortex of hypothyroid animals and decreased in the hypothalamus of hyperthyroid rats.

Original language	English (US)
Pages (from-to)	125-127
Number of pages	3
Journal	European Journal of Pharmacology
Volume	78
Issue number	1
DOIs	https://doi.org/10.1016/0014-2999(82)90381-8
State	Published - Feb 19 1982

Keywords

Dynorphin
Hyperthyroidism
Hypothalamus
Hypothyroidism
Pituitary

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abstract = "Dynorphin is a potent opioid peptide. Using a highly sensitive radioimmunoassay we have measured the levels of immunoreactive (ir) dynorphin in the cortex, hypothalamus, anterior and posterior pituitary in hyperthyroid and hypothyroid rats. Ir dynorphin levels were increased in the cortex of hypothyroid animals and decreased in the hypothalamus of hyperthyroid rats.",

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AU - Morley, John E.

AU - Elson, Michael K.

AU - Levine, Allen S.

AU - Shafer, Rex B.

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AB - Dynorphin is a potent opioid peptide. Using a highly sensitive radioimmunoassay we have measured the levels of immunoreactive (ir) dynorphin in the cortex, hypothalamus, anterior and posterior pituitary in hyperthyroid and hypothyroid rats. Ir dynorphin levels were increased in the cortex of hypothyroid animals and decreased in the hypothalamus of hyperthyroid rats.

KW - Dynorphin

KW - Hyperthyroidism

KW - Hypothalamus

KW - Hypothyroidism

KW - Pituitary

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Levels of immunoreactive dynorphin in brain and pituitary of hyperthyroid and hypothyroid rats

Abstract

Keywords

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