Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

Agriculture & Biology

• Human immunodeficiency virus 1 100%
• RNA-directed DNA polymerase 97%
• mutation rate 88%
• Retroviridae 38%
• mutation 33%
• reverse transcription 19%
• genetic variation 15%
• Lentivirus 11%
• Bovine leukemia virus 11%
• cell free system 9%
• necrosis 7%
• spleen 6%
• peptides 5%
• viruses 5%
• cells 5%
• assays 4%
• infection 4%
• testing 3%
• genes 2%

Medicine & Life Sciences

• RNA-Directed DNA Polymerase 95%
• Mutation Rate 86%
• HIV-1 70%
• Retroviridae 35%
• Human immunodeficiency virus 1 reverse transcriptase 33%
• Genetic Variation 23%
• Mutation 22%
• Trager duck spleen necrosis virus 15%
• Reverse Transcription 14%
• Bovine Leukemia Virus 12%
• Lac Operon 10%
• Cell-Free System 10%
• Lentivirus 9%
• Peptides 5%
• Infections 3%