Lysine substitutions convert a bacterial-agglutinating peptide into a bactericidal peptide that retains anti-lipopolysaccharide activity and low hemolytic activity

Medicine & Life Sciences

• GL13K 100%
• Lysine 43%
• Lipopolysaccharides 38%
• Peptides 28%
• Pseudomonas aeruginosa 9%
• Streptococcus gordonii 7%
• Salivary Proteins and Peptides 7%
• Primary Spontaneous Pneumothorax 7%
• Bacteria 6%
• Porphyromonas gingivalis 6%
• Agglutination 5%
• Hydroxyl Radical 5%
• Gram-Positive Bacteria 5%
• Amino Acid Substitution 5%
• Hemolysis 5%
• Alanine 5%
• Saliva 4%
• Serine 4%
• Sepsis 3%
• Anti-Inflammatory Agents 3%
• Escherichia coli 3%
• Amino Acids 3%
• In Vitro Techniques 2%
• Proteins 1%

Chemical Compounds

• Haemolytic 50%
• Lysine 42%
• Substitution Reaction 27%
• Peptide 25%
• Lysine Residue 9%
• Antiinflammatory 8%
• Serine 8%
• Amino-Acid Residue 7%
• Protein 7%
• Acid 3%
• Application 2%