We studied histology, findings on H-l magnetic resonance (MR) imaging, and correlations of P-31 MR spectroscopy with microe-lectrode pH and pO2 measurements in the BA1112 rhabdomy-osarcoma in WAG/Rij/Y rats. Intratumoral hemorrhage was a prominent feature on MR images and pathologic specimens. Eosinophilic necrosis could be seen microscopically but was not discernible on images. The peaks seen on P-31 MR spectra were similar to those reported in other tumors. The intratumoral pH was neutral despite low pO2 values and P-31 MR evidence for unpaired metabolic status.
- Magnetic resonance imaging
- Magnetic resonance spectroscopy
- Neoplasm histology
- Neoplasm physiology