Meningiomas: Clinical needs and molecular insights

Saskia Peerdeman, Okay Saydam, Connie Jimenez

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Meningiomas are common human brain tumors usually of benign nature. These brain tumors derive from arachnoidal cells associated with brain meninges. The etiology of incidental meningiomas is unknown. A predisposing factor is ionizing radiation. Some genetic syndromes like neurofibromatosis type 2 are associated with meningiomas. Here we highlight the clinical needs and review recent progress made in the field of genomics and proteomics. Finally, we focus on minichromosome maintenance proteins as potential novel markers for early diagnosis of meningioma.

Original languageEnglish (US)
Title of host publicationTumors of the Central Nervous System, Volume 7
Subtitle of host publicationMeningiomas and Schwannomas
PublisherSpringer Netherlands
Pages39-46
Number of pages8
ISBN (Electronic)9789400728943
ISBN (Print)9789400728936
DOIs
StatePublished - Jan 1 2012
Externally publishedYes

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