Metabolism of the tobacco specific nitrosamines, N'-nitrosonornicotine and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.

Medicine & Life Sciences

• N'-nitrosonornicotine 100%
• 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 87%
• Nitrosamines 77%
• Hydroxylation 64%
• Tobacco 53%
• pyridine 18%
• N'-nitrosonornicotine-N-oxide 16%
• 4-hydroxy-4-(3-pyridyl)butanoic acid 15%
• 4-hydroxy-1-(3-pyridyl)-1-butanone 14%
• butyraldehyde 12%
• pyrrolidine 10%
• 1-Butanol 9%
• In Vitro Techniques 9%
• Oxides 8%
• Carcinogens 6%
• Acids 5%