TY - JOUR
T1 - Microdilution aminoglycoside susceptibility testing of Pseudomonas aeruginosa and Escherichia coli
T2 - Correlation between MICs of clinical isolates and quality control organisms
AU - Larson, T. A.
AU - Peterson, L. R.
AU - Gerding, D. N.
PY - 1985
Y1 - 1985
N2 - The monthly variation in geometric mean MICs (GMICs) of amikacin, tobramycin, and gentamicin for Escherichia coli and Pseudomonas aeruginosa laboratory controls and clinical isolates was followed for 30 months. For 19 months, MICs were determined by using Micro-Media system (MMS; Micro-Media Systems, Inc., Potomac, Md.) microdilution panels, and for the other 11 months, MicroScan (MS; American Scientific Products, McGaw Park, Ill.) MIC test panels were used. The aminoglycoside GMICs for control E. coli and P. aeruginosa were significantly lower with the MS system than with the MMS system. A significant correlation was observed between the GMICs for controls and clinical isolates more frequently with the MMS system than with the MS system. Differences are believed to be related to the criteria used in the selection of quality control strains.
AB - The monthly variation in geometric mean MICs (GMICs) of amikacin, tobramycin, and gentamicin for Escherichia coli and Pseudomonas aeruginosa laboratory controls and clinical isolates was followed for 30 months. For 19 months, MICs were determined by using Micro-Media system (MMS; Micro-Media Systems, Inc., Potomac, Md.) microdilution panels, and for the other 11 months, MicroScan (MS; American Scientific Products, McGaw Park, Ill.) MIC test panels were used. The aminoglycoside GMICs for control E. coli and P. aeruginosa were significantly lower with the MS system than with the MMS system. A significant correlation was observed between the GMICs for controls and clinical isolates more frequently with the MMS system than with the MS system. Differences are believed to be related to the criteria used in the selection of quality control strains.
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U2 - 10.1128/jcm.22.5.819-821.1985
DO - 10.1128/jcm.22.5.819-821.1985
M3 - Article
C2 - 3932459
AN - SCOPUS:0022376678
SN - 0095-1137
VL - 22
SP - 819
EP - 821
JO - Journal of clinical microbiology
JF - Journal of clinical microbiology
IS - 5
ER -