TY - JOUR
T1 - Midsagittal cerebral anatomy by magnetic resonance imaging. The importance of slice position and thickness
AU - Coffman, Jeffrey A.
AU - Schwarzkopf, Steven B.
AU - Olson, Stephen C.
AU - Nasrallah, Henry A.
PY - 1989/1/1
Y1 - 1989/1/1
N2 - Several recent studies of psychiatric patients have relied upon magnetic resonance imaging (MRI) to demonstrate features of cerebral anatomy in the midsagittal plane. Methodologies have varied somewhat in relation to thickness and position of planes of view. Due to concerns over the effects of slice thickness and position on measurements, the authors used a multislice thin plane method to assess these effects in 143 individuals (34 controls, 58 schizophrenics, and 51 with bipolar or schizoaffective disorder). Substantial variance in area measurements attributable to slice position emerged, especially in ventricular, cerebral and cerebellar area. Of greater importance would be the demonstrated interaction of position with diagnosis and sex in measures of several regions. The implications of these findings for MRI studies are discussed.
AB - Several recent studies of psychiatric patients have relied upon magnetic resonance imaging (MRI) to demonstrate features of cerebral anatomy in the midsagittal plane. Methodologies have varied somewhat in relation to thickness and position of planes of view. Due to concerns over the effects of slice thickness and position on measurements, the authors used a multislice thin plane method to assess these effects in 143 individuals (34 controls, 58 schizophrenics, and 51 with bipolar or schizoaffective disorder). Substantial variance in area measurements attributable to slice position emerged, especially in ventricular, cerebral and cerebellar area. Of greater importance would be the demonstrated interaction of position with diagnosis and sex in measures of several regions. The implications of these findings for MRI studies are discussed.
KW - Magnetic resonance imaging
KW - Midsagittal cerebral anatomy
KW - Slice position
KW - slice thickness
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U2 - 10.1016/0920-9964(89)90005-4
DO - 10.1016/0920-9964(89)90005-4
M3 - Article
C2 - 2487168
AN - SCOPUS:0024382405
SN - 0920-9964
VL - 2
SP - 287
EP - 294
JO - Schizophrenia Research
JF - Schizophrenia Research
IS - 3
ER -