Multiple sclerosis on steroids

Matthew S. Johnson, Michael S. Lee, Brian R. Younge, Valerie Purvin

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


A 57-year-old man developed acute bilateral vision loss clinically consistent with bilateral optic neuritis. Within 1 month of diagnosis, he developed progressive and severe neurologic dysfunction, and repeat MRI demonstrated enhancement of the optic chiasm and optic tracts, as well as a large enhancing lesion within the right parieto-occipital lobe. Stereotactic-guided brain biopsy demonstrated demyelination consistent with multiple sclerosis. A diagnosis of fulminant multiple sclerosis was made. The patient died within 2 months of diagnosis. Multiple sclerosis and a fulminant subtype known as Marburg disease are discussed.

Original languageEnglish (US)
Pages (from-to)460-466
Number of pages7
JournalSurvey of Ophthalmology
Issue number5
StatePublished - Sep 2010


  • Bilateral visual loss
  • Fulminant
  • Marburg
  • Multiple sclerosis
  • Optic neuritis
  • Treatment


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