Multiple sclerosis on steroids

Matthew S. Johnson; Michael S. Lee; Brian R. Younge; Valerie Purvin

doi:10.1016/j.survophthal.2009.11.002

Multiple sclerosis on steroids

Matthew S. Johnson, Michael S. Lee, Brian R. Younge, Valerie Purvin

Ophthalmology & Visual Neurosciences

Research output: Contribution to journal › Article › peer-review

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Abstract

A 57-year-old man developed acute bilateral vision loss clinically consistent with bilateral optic neuritis. Within 1 month of diagnosis, he developed progressive and severe neurologic dysfunction, and repeat MRI demonstrated enhancement of the optic chiasm and optic tracts, as well as a large enhancing lesion within the right parieto-occipital lobe. Stereotactic-guided brain biopsy demonstrated demyelination consistent with multiple sclerosis. A diagnosis of fulminant multiple sclerosis was made. The patient died within 2 months of diagnosis. Multiple sclerosis and a fulminant subtype known as Marburg disease are discussed.

Original language	English (US)
Pages (from-to)	460-466
Number of pages	7
Journal	Survey of Ophthalmology
Volume	55
Issue number	5
DOIs	https://doi.org/10.1016/j.survophthal.2009.11.002
State	Published - Sep 2010

Keywords

Bilateral visual loss
Fulminant
Marburg
Multiple sclerosis
Optic neuritis
Treatment

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.survophthal.2009.11.002

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title = "Multiple sclerosis on steroids",

abstract = "A 57-year-old man developed acute bilateral vision loss clinically consistent with bilateral optic neuritis. Within 1 month of diagnosis, he developed progressive and severe neurologic dysfunction, and repeat MRI demonstrated enhancement of the optic chiasm and optic tracts, as well as a large enhancing lesion within the right parieto-occipital lobe. Stereotactic-guided brain biopsy demonstrated demyelination consistent with multiple sclerosis. A diagnosis of fulminant multiple sclerosis was made. The patient died within 2 months of diagnosis. Multiple sclerosis and a fulminant subtype known as Marburg disease are discussed.",

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AU - Younge, Brian R.

AU - Purvin, Valerie

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AB - A 57-year-old man developed acute bilateral vision loss clinically consistent with bilateral optic neuritis. Within 1 month of diagnosis, he developed progressive and severe neurologic dysfunction, and repeat MRI demonstrated enhancement of the optic chiasm and optic tracts, as well as a large enhancing lesion within the right parieto-occipital lobe. Stereotactic-guided brain biopsy demonstrated demyelination consistent with multiple sclerosis. A diagnosis of fulminant multiple sclerosis was made. The patient died within 2 months of diagnosis. Multiple sclerosis and a fulminant subtype known as Marburg disease are discussed.

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KW - Marburg

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KW - Optic neuritis

KW - Treatment

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Multiple sclerosis on steroids

Abstract

Keywords

UN SDGs

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