TY - JOUR
T1 - Nanowarming using Au-tipped Co35Fe65 ferromagnetic nanowires
AU - Shore, Daniel
AU - Ghemes, Adrian
AU - Dragos-Pinzaru, Oana
AU - Gao, Zhe
AU - Shao, Qi
AU - Sharma, Anirudh
AU - Um, Joseph
AU - Tabakovic, Ibro
AU - Bischof, John C.
AU - Stadler, Bethanie J.H.
N1 - Publisher Copyright:
© 2019 The Royal Society of Chemistry.
PY - 2019/8/21
Y1 - 2019/8/21
N2 - Ferromagnetic Co35Fe65, Fe, Co, and Ni nanowires have high saturation magnetizations (Ms) and magnetic anisotropies, making them ideal for magnetic heating in an alternating magnetic field (AMF). Here, Au-tipped nanowires were coated with polyethylene glycol (PEG) and specific absorption rates (SAR) were measured in glycerol. SAR increased when using metals with increasing Ms (Co35Fe65 > Fe > Co > Ni), reaching 1610 ± 20 W g-1 metal at 1 mg metal per ml glycerol for Co35Fe65 nanowires using 190 kHz and 20 kA m-1. Aligning these nanowires parallel to the AMF increased SAR up to 2010 W g-1 Co35Fe65. Next, Co35Fe65 nanowires were used to nanowarm vitrified VS55, a common cryoprotective agent (CPA).Nanowarming rates up to 1000 °C min-1 (5 mg Co35Fe65 per ml VS55) were achieved, which is 20× faster than the critical warming rate (50 °C min-1) for VS55 and other common CPAs. Human dermal fibroblast cells exposed to VS55, and Co35Fe65 nanowire concentrations of 0, 1 and 2.5 mg Fe per ml all showed similar cell viability, indicating that the nanowires had minimal cytotoxicity. With the ability to provide rapid and uniform heating, ferromagnetic nanowires have excellent potential for nanowarming cryopreserved tissues.
AB - Ferromagnetic Co35Fe65, Fe, Co, and Ni nanowires have high saturation magnetizations (Ms) and magnetic anisotropies, making them ideal for magnetic heating in an alternating magnetic field (AMF). Here, Au-tipped nanowires were coated with polyethylene glycol (PEG) and specific absorption rates (SAR) were measured in glycerol. SAR increased when using metals with increasing Ms (Co35Fe65 > Fe > Co > Ni), reaching 1610 ± 20 W g-1 metal at 1 mg metal per ml glycerol for Co35Fe65 nanowires using 190 kHz and 20 kA m-1. Aligning these nanowires parallel to the AMF increased SAR up to 2010 W g-1 Co35Fe65. Next, Co35Fe65 nanowires were used to nanowarm vitrified VS55, a common cryoprotective agent (CPA).Nanowarming rates up to 1000 °C min-1 (5 mg Co35Fe65 per ml VS55) were achieved, which is 20× faster than the critical warming rate (50 °C min-1) for VS55 and other common CPAs. Human dermal fibroblast cells exposed to VS55, and Co35Fe65 nanowire concentrations of 0, 1 and 2.5 mg Fe per ml all showed similar cell viability, indicating that the nanowires had minimal cytotoxicity. With the ability to provide rapid and uniform heating, ferromagnetic nanowires have excellent potential for nanowarming cryopreserved tissues.
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U2 - 10.1039/c9nr01182j
DO - 10.1039/c9nr01182j
M3 - Article
C2 - 31287480
AN - SCOPUS:85070799945
SN - 2040-3364
VL - 11
SP - 14607
EP - 14615
JO - Nanoscale
JF - Nanoscale
IS - 31
ER -