O2activation and selective phenolate ortho hydroxylation by an unsymmetric dicopper μη1: η1-peroxido Complex

Isaac Garcia-Bosch, Anna Company, Jonathan R. Frisch, Miquel Torrent-Sucarrat, Mar Cardellach, Ilaria Gamba, Mireia Güell, Luigi Casella, Lawrence Que, Xavi Ribas, Josep M. Luis, Miquel Costas

Research output: Contribution to journalArticlepeer-review

86 Scopus citations

Abstract

Unusual reactivity: A novel unsymmetric dicopper complex gives rise to the unsymmetric species 1-O2having a μ-η1: η1-O2binding mode and reactivity patterns not previously observed for symmetric analogues. It is unreactive in oxygen atom transfer reactions, but it can selectively bind phenolate and mediate its Ortho hydroxylation, thereby demonstrat-ing a conceptually different tyrosinase model with exquisite selectivity. (Figure Presented)

Original languageEnglish (US)
Pages (from-to)2406-2409
Number of pages4
JournalAngewandte Chemie - International Edition
Volume49
Issue number13
DOIs
StatePublished - Mar 22 2010

Keywords

  • Bioinorganic chemistry
  • Dioxygen ligands
  • O-o activation
  • Oxidation

Fingerprint Dive into the research topics of 'O<sub>2</sub>activation and selective phenolate ortho hydroxylation by an unsymmetric dicopper μη<sup>1</sup>: η<sup>1</sup>-peroxido Complex'. Together they form a unique fingerprint.

Cite this