Palladium-Catalyzed Polyene Cyclizations of Trienyl Triflates

Nancy E Carpenter, David J. Kucera, Larry E. Overman

Research output: Contribution to journalLetterpeer-review

219 Scopus citations

Abstract

Spirotricyclic dienones are conveniently prepared by palladium-catalyzed cyclizations of enol triflate derivatives of 2-dienyl-l,3-cyclohexanediones. The use of chiral (nonracemic) ligands allows assembly of these products with moderate enantioselectivity, demonstrating a potentially powerful new method for catalytic asymmetric construction of quaternary carbon stereocenters.

Original languageEnglish (US)
Pages (from-to)5846-5848
Number of pages3
JournalJournal of Organic Chemistry
Volume54
Issue number25
DOIs
StatePublished - Dec 1 1989
Externally publishedYes

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