Over the past decade, there has been a significant increase in the number of patients with a variety of malignant and nonmalignant disorders referred for bone marrow transplantation. Despite numerous advances in the care of such patients after allogeneic bone marrow transplantation, acute and chronic graft-vs.-host disease continues to be a prinicipal cause of morbidity and mortality. In this article, we will present an overview of the pathogenesis, clinical presentation, and pathological manifestations of these two major complications.
|Original language||English (US)|
|Number of pages||17|
|Journal||American Journal of Pediatric Hematology/Oncology|
|State||Published - Jan 1 1989|
- Bone marrow transplantation
- Graft-vs.-host disease