TY - JOUR
T1 - Perfusion thallium imaging of type I diabetes patients with end stage renal disease
T2 - Comparison of oral and intravenous dipyridamole administration
AU - Boudreau, Robert J.
AU - Strony, John T.
AU - DuCret, Rene P.
AU - Kuni, Christopher C.
AU - Wang, Yang
AU - Wilson, Robert F
AU - Schwartz, Jeffrey S.
AU - Castaneda-Zuniga, Wilfrido R.
PY - 1990/4
Y1 - 1990/4
N2 - Eighty patients with type I diabetes and end stage renal disease were prospectively evaluated for coronary artery disease with dipyridamole-thallium-201 scintigraphy and quantitative coronary angiography. Forty patients received dipyridamole orally, and 40 received it intravenously. The prevalence of coronary artery disease was 53%. There were no significant differences in the accuracy of the two dipyridamole tests (sensitivity = 85%, specificity = 85%, accuracy = 85% for the oral group; sensitivity = 86%, specificity = 72%, accuracy = 79% for the intravenous group). Combining the 80 patients into a single group gave a sensitivity of 86%, a specificity of 79%, and an accuracy of 83% for the detection of coronary disease. Although the accuracy of this test in this patient population was similar to that previously reported for other groups, the prevalence of disease was high and resulted in a low predictive value of a negative test (83%).
AB - Eighty patients with type I diabetes and end stage renal disease were prospectively evaluated for coronary artery disease with dipyridamole-thallium-201 scintigraphy and quantitative coronary angiography. Forty patients received dipyridamole orally, and 40 received it intravenously. The prevalence of coronary artery disease was 53%. There were no significant differences in the accuracy of the two dipyridamole tests (sensitivity = 85%, specificity = 85%, accuracy = 85% for the oral group; sensitivity = 86%, specificity = 72%, accuracy = 79% for the intravenous group). Combining the 80 patients into a single group gave a sensitivity of 86%, a specificity of 79%, and an accuracy of 83% for the detection of coronary disease. Although the accuracy of this test in this patient population was similar to that previously reported for other groups, the prevalence of disease was high and resulted in a low predictive value of a negative test (83%).
KW - Coronary vessels, diseases, 54.76
KW - Coronary vessels, radionuclide studies, 54.1299
KW - Diabetes mellitus, complications, 96.724
KW - Dipyridamole
KW - Heart, effects of drugs on
KW - Kidney, failure, 81.79
KW - Thallium, radioactive
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U2 - 10.1148/radiology.175.1.2315467
DO - 10.1148/radiology.175.1.2315467
M3 - Review article
C2 - 2315467
AN - SCOPUS:0025305472
SN - 0033-8419
VL - 175
SP - 103
EP - 105
JO - Radiology
JF - Radiology
IS - 1
ER -
