Pharmacological and industrial chalenge: Deciphering extracircadian rhythmic signatures in us and around us. Review

F. Halberg, G. Cornélissen, G. Katinas, R. P. Sonkowsky, K. Yasaka, M. Herold, F. Perfetto, R. Tarquini, M. Engebretson, O. Schwartzkopff, E. E. Bakken, J. Siegelová, B. Fišer

Research output: Contribution to journalReview articlepeer-review


The scope of chronobiological diagnosis and treatment in biology and medicine can be extended from a consideration of circadian systems to time structures, i.e., chronomes, and thereby to introduce chronomics, the mapping of chronomes, into applications for medical devices and pharmaceutical industries and the software companies serving them. The task of lifelong monitoring, apart from providing a more solid preventive health care, further serves to a timely and timed treatment and the elucidation of basic aspects of variability in and around us, which may be useful to ecology and chronoastrobiology.

Original languageEnglish (US)
Pages (from-to)71-80
Number of pages10
JournalScripta Medica Facultatis Medicae Universitatis Brunensis Masarykianae
Issue number2
StatePublished - 2002


  • Biological rhythms
  • Cardiovascular parameters
  • Circadian rhythm
  • Circaseptan rhythm

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