Pharmacology of highly selective, non-peptide delta opioid receptor antagonists

A. E. Takemori; M. Sofuoglu; M. Sultana; H. Nagase; P. S. Portoghese

Pharmacology of highly selective, non-peptide delta opioid receptor antagonists

A. E. Takemori, M. Sofuoglu, M. Sultana, H. Nagase, P. S. Portoghese

Medicinal Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

10 Scopus citations

Abstract

Naltrindole (NTI) and three of its analogues, N-Me-NTI, oxymorphindole (OMI), and the benzofuran analogue (NTB) were examined in the opioid receptor binding and antinociceptive assays and they were found to have a selectivity profile similar to that in smooth muscle assays, i.e. very selective for δ-opioid receptors.

Original language	English (US)
Title of host publication	New leads in opioid research
Subtitle of host publication	proceedings of the International Narcotics Research Conference. ICS914
Editors	J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus, J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus
Publisher	Elsevier Science Publishers B.V.
Number of pages	1
ISBN (Print)	044481213X
State	Published - Jan 1 1990
Event	The International Narcotics Research Conference - Duration: Jul 8 1989 → Jul 13 1989

Publication series

Name	New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914

Other

Other	The International Narcotics Research Conference
Period	7/8/89 → 7/13/89

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Takemori, A. E., Sofuoglu, M., Sultana, M., Nagase, H., & Portoghese, P. S. (1990). Pharmacology of highly selective, non-peptide delta opioid receptor antagonists. In J. M. Van Ree, A. H. Mulder, V. M. Wiegant, T. B. Van Wimersma Greidanus, J. M. Van Ree, A. H. Mulder, V. M. Wiegant, & T. B. Van Wimersma Greidanus (Eds.), New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914 (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914). Elsevier Science Publishers B.V..

Pharmacology of highly selective, non-peptide delta opioid receptor antagonists. / Takemori, A. E.; Sofuoglu, M.; Sultana, M. et al.
New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. ed. / J.M. Van Ree; A.H. Mulder; V.M. Wiegant; T.B. Van Wimersma Greidanus; J.M. Van Ree; A.H. Mulder; V.M. Wiegant; T.B. Van Wimersma Greidanus. Elsevier Science Publishers B.V., 1990. (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Takemori, AE, Sofuoglu, M, Sultana, M, Nagase, H & Portoghese, PS 1990, Pharmacology of highly selective, non-peptide delta opioid receptor antagonists. in JM Van Ree, AH Mulder, VM Wiegant, TB Van Wimersma Greidanus, JM Van Ree, AH Mulder, VM Wiegant & TB Van Wimersma Greidanus (eds), New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914, Elsevier Science Publishers B.V., The International Narcotics Research Conference, 7/8/89.

Takemori AE, Sofuoglu M, Sultana M, Nagase H, Portoghese PS. Pharmacology of highly selective, non-peptide delta opioid receptor antagonists. In Van Ree JM, Mulder AH, Wiegant VM, Van Wimersma Greidanus TB, Van Ree JM, Mulder AH, Wiegant VM, Van Wimersma Greidanus TB, editors, New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. Elsevier Science Publishers B.V. 1990. (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914).

Takemori, A. E. ; Sofuoglu, M. ; Sultana, M. et al. / Pharmacology of highly selective, non-peptide delta opioid receptor antagonists. New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. editor / J.M. Van Ree ; A.H. Mulder ; V.M. Wiegant ; T.B. Van Wimersma Greidanus ; J.M. Van Ree ; A.H. Mulder ; V.M. Wiegant ; T.B. Van Wimersma Greidanus. Elsevier Science Publishers B.V., 1990. (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914).

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Pharmacology of highly selective, non-peptide delta opioid receptor antagonists

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