Plasma Arginine Vasopressin in Hyponatremic Patients with Heart Failure

Steven Goldsmith; Jay N Cohn; Gary S Francis; Allen Cowley; S. Smitz; J. J. Legros; J. L. Waucquez; P. A. Phillips; B. J. Rolls; J. G.G. Ledingham; Victoria L. Szatalowicz; Patricia E. Arnold; Cidio Chaimovitz; Daniel G. Bichet; Tomas Berl; Robert W. Schrier

doi:10.1056/NEJM198112103052412

Plasma Arginine Vasopressin in Hyponatremic Patients with Heart Failure

Steven Goldsmith, Jay N Cohn, Gary S Francis, Allen Cowley, S. Smitz, J. J. Legros, J. L. Waucquez, P. A. Phillips, B. J. Rolls, J. G.G. Ledingham, Victoria L. Szatalowicz, Patricia E. Arnold, Cidio Chaimovitz, Daniel G. Bichet, Tomas Berl, Robert W. Schrier

Medicine - Cardiology Division

Research output: Contribution to journal › Letter › peer-review

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Abstract

To the Editor: We offer the following comments in reference to the paper by Szatalowicz et al.¹ in the July 30 issue, reporting detectable arginine vasopressin (AVP) levels in some hyponatremic patients with heart failure. Although 3.04±0.84 pg per milliliter was the mean value for AVP in the group with “detectable” levels, this number is somewhat misleading because of the presence of several very high values. Two thirds of the levels were actually below 2.0 pg per milliliter, and half of those were under 1.0 pg per milliliter. Thus, in most subjects, even in this group, AVP was nearly completely.

Original language	English (US)
Pages (from-to)	1470-1472
Number of pages	3
Journal	New England Journal of Medicine
Volume	305
Issue number	24
DOIs	https://doi.org/10.1056/NEJM198112103052412
State	Published - Dec 10 1981

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Goldsmith, S., Cohn, J. N., Francis, G. S., Cowley, A., Smitz, S., Legros, J. J., Waucquez, J. L., Phillips, P. A., Rolls, B. J., Ledingham, J. G. G., Szatalowicz, V. L., Arnold, P. E., Chaimovitz, C., Bichet, D. G., Berl, T., & Schrier, R. W. (1981). Plasma Arginine Vasopressin in Hyponatremic Patients with Heart Failure. New England Journal of Medicine, 305(24), 1470-1472. https://doi.org/10.1056/NEJM198112103052412

Goldsmith, S, Cohn, JN, Francis, GS, Cowley, A, Smitz, S, Legros, JJ, Waucquez, JL, Phillips, PA, Rolls, BJ, Ledingham, JGG, Szatalowicz, VL, Arnold, PE, Chaimovitz, C, Bichet, DG, Berl, T & Schrier, RW 1981, 'Plasma Arginine Vasopressin in Hyponatremic Patients with Heart Failure', New England Journal of Medicine, vol. 305, no. 24, pp. 1470-1472. https://doi.org/10.1056/NEJM198112103052412

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abstract = "To the Editor: We offer the following comments in reference to the paper by Szatalowicz et al.1 in the July 30 issue, reporting detectable arginine vasopressin (AVP) levels in some hyponatremic patients with heart failure. Although 3.04±0.84 pg per milliliter was the mean value for AVP in the group with “detectable” levels, this number is somewhat misleading because of the presence of several very high values. Two thirds of the levels were actually below 2.0 pg per milliliter, and half of those were under 1.0 pg per milliliter. Thus, in most subjects, even in this group, AVP was nearly completely.",

author = "Steven Goldsmith and Cohn, {Jay N} and Francis, {Gary S} and Allen Cowley and S. Smitz and Legros, {J. J.} and Waucquez, {J. L.} and Phillips, {P. A.} and Rolls, {B. J.} and Ledingham, {J. G.G.} and Szatalowicz, {Victoria L.} and Arnold, {Patricia E.} and Cidio Chaimovitz and Bichet, {Daniel G.} and Tomas Berl and Schrier, {Robert W.}",

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AU - Goldsmith, Steven

AU - Cohn, Jay N

AU - Francis, Gary S

AU - Cowley, Allen

AU - Smitz, S.

AU - Legros, J. J.

AU - Waucquez, J. L.

AU - Phillips, P. A.

AU - Rolls, B. J.

AU - Ledingham, J. G.G.

AU - Szatalowicz, Victoria L.

AU - Arnold, Patricia E.

AU - Chaimovitz, Cidio

AU - Bichet, Daniel G.

AU - Berl, Tomas

AU - Schrier, Robert W.

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N2 - To the Editor: We offer the following comments in reference to the paper by Szatalowicz et al.1 in the July 30 issue, reporting detectable arginine vasopressin (AVP) levels in some hyponatremic patients with heart failure. Although 3.04±0.84 pg per milliliter was the mean value for AVP in the group with “detectable” levels, this number is somewhat misleading because of the presence of several very high values. Two thirds of the levels were actually below 2.0 pg per milliliter, and half of those were under 1.0 pg per milliliter. Thus, in most subjects, even in this group, AVP was nearly completely.

AB - To the Editor: We offer the following comments in reference to the paper by Szatalowicz et al.1 in the July 30 issue, reporting detectable arginine vasopressin (AVP) levels in some hyponatremic patients with heart failure. Although 3.04±0.84 pg per milliliter was the mean value for AVP in the group with “detectable” levels, this number is somewhat misleading because of the presence of several very high values. Two thirds of the levels were actually below 2.0 pg per milliliter, and half of those were under 1.0 pg per milliliter. Thus, in most subjects, even in this group, AVP was nearly completely.

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Plasma Arginine Vasopressin in Hyponatremic Patients with Heart Failure

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