Plasma exchange versus intravenous immunoglobulin treatment in myasthenic crisis

Adnan I. Qureshi, M. A. Choudhry, M. S. Akbar, Y. Mohammad, H. C. Chua, A. M. Yahia, J. A. Ulatowski, D. A. Krendel, R. T. Leshner

Research output: Contribution to journalArticlepeer-review

132 Scopus citations

Abstract

We performed a retrospective multicenter chart review to compare the efficacy and tolerance of plasma exchange (PE) and intravenous immunoglobulin (IVIg) in treatment of 54 episodes of myasthenic crisis. After adjustment for other variables, PE (compared with IVIg) was associated with a superior ventilatory status at 2 weeks (partial F = 6.2, p = 0.02) and 1 month functional outcome (partial F = 4.5, p = 0.04). However, the complication rate was higher with PE compared with IVIg (13 versus 5 episodes, p = 0.07).

Original languageEnglish (US)
Pages (from-to)629-632
Number of pages4
JournalNeurology
Volume52
Issue number3
DOIs
StatePublished - Feb 1999

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