Plasma exchange versus intravenous immunoglobulin treatment in myasthenic crisis

Adnan I. Qureshi; M. A. Choudhry; M. S. Akbar; Y. Mohammad; H. C. Chua; A. M. Yahia; J. A. Ulatowski; D. A. Krendel; R. T. Leshner

doi:10.1212/wnl.52.3.629

Plasma exchange versus intravenous immunoglobulin treatment in myasthenic crisis

Adnan I. Qureshi, M. A. Choudhry, M. S. Akbar, Y. Mohammad, H. C. Chua, A. M. Yahia, J. A. Ulatowski, D. A. Krendel, R. T. Leshner

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164 Scopus citations

Abstract

We performed a retrospective multicenter chart review to compare the efficacy and tolerance of plasma exchange (PE) and intravenous immunoglobulin (IVIg) in treatment of 54 episodes of myasthenic crisis. After adjustment for other variables, PE (compared with IVIg) was associated with a superior ventilatory status at 2 weeks (partial F = 6.2, p = 0.02) and 1 month functional outcome (partial F = 4.5, p = 0.04). However, the complication rate was higher with PE compared with IVIg (13 versus 5 episodes, p = 0.07).

Original language	English (US)
Pages (from-to)	629-632
Number of pages	4
Journal	Neurology
Volume	52
Issue number	3
DOIs	https://doi.org/10.1212/wnl.52.3.629
State	Published - Feb 1999
Externally published	Yes

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title = "Plasma exchange versus intravenous immunoglobulin treatment in myasthenic crisis",

abstract = "We performed a retrospective multicenter chart review to compare the efficacy and tolerance of plasma exchange (PE) and intravenous immunoglobulin (IVIg) in treatment of 54 episodes of myasthenic crisis. After adjustment for other variables, PE (compared with IVIg) was associated with a superior ventilatory status at 2 weeks (partial F = 6.2, p = 0.02) and 1 month functional outcome (partial F = 4.5, p = 0.04). However, the complication rate was higher with PE compared with IVIg (13 versus 5 episodes, p = 0.07).",

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AU - Qureshi, Adnan I.

AU - Choudhry, M. A.

AU - Akbar, M. S.

AU - Mohammad, Y.

AU - Chua, H. C.

AU - Yahia, A. M.

AU - Ulatowski, J. A.

AU - Krendel, D. A.

AU - Leshner, R. T.

PY - 1999/2

Y1 - 1999/2

N2 - We performed a retrospective multicenter chart review to compare the efficacy and tolerance of plasma exchange (PE) and intravenous immunoglobulin (IVIg) in treatment of 54 episodes of myasthenic crisis. After adjustment for other variables, PE (compared with IVIg) was associated with a superior ventilatory status at 2 weeks (partial F = 6.2, p = 0.02) and 1 month functional outcome (partial F = 4.5, p = 0.04). However, the complication rate was higher with PE compared with IVIg (13 versus 5 episodes, p = 0.07).

AB - We performed a retrospective multicenter chart review to compare the efficacy and tolerance of plasma exchange (PE) and intravenous immunoglobulin (IVIg) in treatment of 54 episodes of myasthenic crisis. After adjustment for other variables, PE (compared with IVIg) was associated with a superior ventilatory status at 2 weeks (partial F = 6.2, p = 0.02) and 1 month functional outcome (partial F = 4.5, p = 0.04). However, the complication rate was higher with PE compared with IVIg (13 versus 5 episodes, p = 0.07).

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Plasma exchange versus intravenous immunoglobulin treatment in myasthenic crisis

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