Polymyxin B nonapeptide: Conformations in water and in the lipopolysaccharide-bound state determined by two-dimensional NMR and molecular dynamics

Engineering & Materials Science

• Peptides 68%
• Conformations 65%
• Nuclear magnetic resonance 61%
• Molecular dynamics 57%
• Dipeptides 42%
• Bacilli 37%
• Lipids 34%
• Toxicity 30%
• Water 27%
• Derivatives 21%
• Experiments 9%

Medicine & Life Sciences

• polymyxin B nonapeptide 100%
• Molecular Dynamics Simulation 57%
• Lipopolysaccharides 44%
• Water 34%
• Polymyxin B 22%
• Paenibacillus polymyxa 15%
• Polymyxins 12%
• Lipid A 11%
• Dipeptides 11%
• Peptides 11%
• Endotoxins 8%
• Therapeutics 1%

Chemical Compounds

• Polymyxin 74%
• Two-Dimensional NMR 53%
• Molecular Dynamics 38%
• Lipopolysaccharide 24%
• Endotoxin 9%
• Nuclear Overhauser Effect 8%
• Peptide 8%
• Neutralization 7%
• Dipeptide 7%
• Compound Mobility 5%
• Antimicrobial Agent 5%
• Lipid 5%
• Aqueous Solution 3%
• Reduction 3%