Abstract
Purpose: To aid nurses in dosing sufentanil sublingual tablet (SST) 30 mcg administered via a single-dose applicator, dosing requirements and efficacy of SST 30 mcg were analyzed across age, sex, race, and body mass index subgroups. Design: Patient characteristics were pooled from three postoperative studies (two placebo-controlled and one open-label) and one open-label emergency department study. Drug dosing and efficacy data were pooled from the postoperative studies. Methods: Efficacy was assessed through summed pain intensity difference to baseline during 12 hours across subgroups. Findings: Mean (standard deviation) drug doses administered from 0 to 12 hours was 3.9 (2.0) for SST 30 mcg and was less frequent for older (≥65 years) versus younger patients. The summed pain intensity difference to baseline during 12 hours was superior with SST 30 mcg versus placebo across all subgroups. Conclusions: SST 30 mcg is a sublingual opioid analgesic with efficacy across demographic subgroups.
Original language | English (US) |
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Pages (from-to) | 22-28 |
Number of pages | 7 |
Journal | Journal of Perianesthesia Nursing |
Volume | 35 |
Issue number | 1 |
DOIs | |
State | Published - Feb 2020 |
Bibliographical note
Publisher Copyright:© 2019 The Authors
Keywords
- acute pain
- analgesia
- opioid
- sublingual