Practice patterns and recommendations for pediatric image-guided radiotherapy: A Children's Oncology Group report

Chia ho Hua, Tamara Z. Vern-Gross, Clayton B. Hess, Arthur J. Olch, Parham Alaei, Vythialingam Sathiaseelan, Jun Deng, Kenneth Ulin, Fran Laurie, Mahesh Gopalakrishnan, Natia Esiashvili, Suzanne L. Wolden, Matthew J. Krasin, Thomas E. Merchant, Sarah S. Donaldson, Thomas J. FitzGerald, Louis S. Constine, David C. Hodgson, Daphne A. Haas-Kogan, Anita MahajanNadia N. Laack, Karen J. Marcus, Paige A. Taylor, Verity A. Ahern, David S. Followill, Jeffrey C. Buchsbaum, John C. Breneman, John A. Kalapurakal

Research output: Contribution to journalArticlepeer-review


This report by the Radiation Oncology Discipline of Children's Oncology Group (COG) describes the practice patterns of pediatric image-guided radiotherapy (IGRT) based on a member survey and provides practice recommendations accordingly. The survey comprised of 11 vignettes asking clinicians about their recommended treatment modalities, IGRT preferences, and frequency of in-room verification. Technical questions asked physicists about imaging protocols, dose reduction, setup correction, and adaptive therapy. In this report, the COG Radiation Oncology Discipline provides an IGRT modality/frequency decision tree and the expert guidelines for the practice of ionizing image guidance in pediatric radiotherapy patients.

Original languageEnglish (US)
Article numbere28629
JournalPediatric Blood and Cancer
Issue number10
StatePublished - Oct 1 2020

Bibliographical note

Funding Information:
The Children's Oncology Group is supported by the National Cancer Institute of the National Institutes of Health under award number NCTN Operations Center Grant U10 CA180886. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Funding Information:
The authors thank Ms. Heidi M. Pusztay from COG for her assistance with the questionnaire and Keith A. Laycock, PhD, ELS, for scientific editing of the manuscript. We acknowledge the support by NCI/NIH grant U24 CA180803 to the Imaging and Radiation Oncology Core.


  • COG
  • IGRT
  • pediatric patients
  • practice patterns
  • radiation oncology

PubMed: MeSH publication types

  • Journal Article
  • Research Support, N.I.H., Extramural

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