Preventing Congenital Cytomegalovirus Infection: Protection to a 'T'

Mark R. Schleiss

doi:10.1016/j.tim.2016.01.007

Preventing Congenital Cytomegalovirus Infection: Protection to a 'T'

Mark R. Schleiss

Pediatrics - Infectious Disease

Research output: Contribution to journal › Short survey › peer-review

8 Scopus citations

Abstract

A lack of knowledge about the correlates of maternal immunity required for protection of the placenta and fetus against congenital cytomegalovirus (CMV) transmission has complicated vaccine development. New work from Bialas and colleagues demonstrates a critical role for maternal CD4⁺ T cells in controlling viremia and preventing CMV-associated fetal disease.

Original language	English (US)
Pages (from-to)	170-172
Number of pages	3
Journal	Trends in Microbiology
Volume	24
Issue number	3
DOIs	https://doi.org/10.1016/j.tim.2016.01.007
State	Published - Mar 1 2016

Bibliographical note

Publisher Copyright:
© 2016.

Keywords

Animal models
Congenital cytomegalovirus infection
Cytomegalovirus immunity
Cytomegalovirus vaccine
Pentameric complex
Placenta

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10.1016/j.tim.2016.01.007

http://europepmc.org/articles/pmc4836615

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abstract = "A lack of knowledge about the correlates of maternal immunity required for protection of the placenta and fetus against congenital cytomegalovirus (CMV) transmission has complicated vaccine development. New work from Bialas and colleagues demonstrates a critical role for maternal CD4+ T cells in controlling viremia and preventing CMV-associated fetal disease.",

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KW - Placenta

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Preventing Congenital Cytomegalovirus Infection: Protection to a 'T'

Abstract

Bibliographical note

Keywords

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