Prognostic value of positive lymph nodes in rectal cancer

Manuel R. Moran, Edwin C. James, David A. Rothenberger, Stanley M. Goldberg

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Abdominal "curative" resections for rectal cancer in 109 patients with positive lymph nodes were prospectively studied. The best subdivision of patients for predicting outcome was into 1-3 and >3 positive lymph node groups. Comparison with patients with >3 positive lymph nodes demonstrated that patients with 1-3 positive nodes had less local (35.0 percentvs.13.0 percent;P=0.007) and less distant recurrences (45.0 percentvs. 26.0 percent;P=0.04) and had much better crude five-year survival (58.2 percentvs. 17.0 percent;P< 0.0001). For predicting postsurgical outcome in patients with positive lymph nodes, the results justify subdividing patients into the following two prognostic subgroups: 1) those with 1-3 involved lymph nodes and 2) those with metastatic tumor in four or more lymph nodes.

Original languageEnglish (US)
Pages (from-to)579-581
Number of pages3
JournalDiseases of the Colon & Rectum
Volume35
Issue number6
DOIs
StatePublished - Jun 1992

Keywords

  • Metastatic lymph nodes
  • Rectal cancer
  • Recurrent rectal cancer
  • Staging

Fingerprint Dive into the research topics of 'Prognostic value of positive lymph nodes in rectal cancer'. Together they form a unique fingerprint.

Cite this